Affiliation:
1. Department of Biological Sciences, Lehigh University, Bethlehem, Pennsylvania
Abstract
This work reveals a physiologically relevant form of activity pairing in coupled neurons that results in long-term potentiation of mammalian electrical synapses. These findings, in combination with previous work, allow the authors to propose a bidirectional calcium-based rule for plasticity of electrical synapses, similar to those demonstrated for chemical synapses. These new insights inform the field on how electrical synapse plasticity may modify the neural circuits that incorporate them.
Funder
Whitehall Foundation
National Science Foundation
Publisher
American Physiological Society
Subject
Physiology,General Neuroscience
Cited by
10 articles.
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