The Quest for Speed: Muscles Built for High-Frequency Contractions

Author:

Rome Lawrence C.1,Lindstedt Stan L.1

Affiliation:

1. L. C. Rome is in the Department of Biology of the University of Pennsylvania, Philadelphia, PA 19104; S. L. Lindstedt is in the Dept. of Biological Sciences at Northern Arizona University, Flagstaff, AZ 86011.

Abstract

Vertebrate sound-producing muscles can contract at frequencies greater than 100 Hz, a feat impossible in locomotory muscles. This is not accomplished by unique proteins or structures but by qualitative shifts in isoforms and quantitative reapportionment of structures. Speed comes with costs and trade-offs, however, that restrict how a muscle can be used.

Publisher

American Physiological Society

Subject

Physiology

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