The Glutamine/Glutamate Couplet and Cellular Function-Reference-Cited by-同舟云学术

The Glutamine/Glutamate Couplet and Cellular Function

Published:2001-08 Issue:4 Volume:16 Page:157-160
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Welbourne Tomas¹,Routh Robert²,Yudkoff Marc³,Nissim Itzhak³

Affiliation:

1. Departments of Molecular and Cellular Physiology and

2. Molecular and Cellular Pathology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130; and

3. Division of Child Development and Rehabilitation, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104-4318

Abstract

All cells require glutamine as a nitrogen donor as well as an energy source for cell-specific functions. Understanding how glutamine utilization is metered to these demands is fundamental to basic cell processes as well as to therapeutic manipulation of regulatory mechanisms. The regulatory role of the glutamine/glutamate couplet in cellular function is illustrated for acid-base homeostasis and for production of the extracellular matrix.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiologyonline.2001.16.4.157

Reference19 articles.

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