Bile acid metabolism and circadian rhythms

Author:

Yang Yunxia1,Zhang Jianfa1ORCID

Affiliation:

1. Center for Molecular Metabolism, Nanjing University of Science and Technology, Nanjing, China

Abstract

Circadian rhythms are biological systems that synchronize cellular circadian oscillators and regulate nutrient absorption and utilization. Bile acids are important modulators that facilitate nutrient absorption and regulate energy metabolism. Bile acid metabolism and circadian rhythms are related to metabolic diseases, and their intersections have not been summarized clearly up to now. This review summarizes the molecular association between circadian rhythms and bile acid metabolism and points out future perspectives and potential therapeutic targets in metabolic diseases.

Funder

National Natural Science Foundation of China

Publisher

American Physiological Society

Subject

Physiology (medical),Gastroenterology,Hepatology,Physiology

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