Predicting oxygen tension along the ureter

Author:

Lee Chang-Joon12ORCID,Gardiner Bruce S.12,Evans Roger G.3ORCID,Smith David W.2ORCID

Affiliation:

1. College of Science, Health, Engineering and Education, Murdoch University, Perth, Western Australia, Australia

2. Faculty of Engineering and Mathematical Sciences, The University of Western Australia, Perth, Western Australia, Australia

3. Cardiovascular Disease Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Victoria, Australia

Abstract

Measurement of bladder urine oxygen tension has been proposed as a new method to potentially detect the risk of acute kidney injury in patients. A computational model of oxygen exchange between urine bolus and ureteral tissue shows that it may be technically possible to determine the risk of acute kidney injury based on the measurement of bladder urine oxygen tension, provided that the measurement data are properly interpreted via a computational model.

Funder

Western Australia Department of Health

Department of Health, Australian Government | National Health and Medical Research Council

Publisher

American Physiological Society

Subject

Physiology

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