Expression of claudin-8 is induced by aldosterone in renal collecting duct principal cells-Reference-Cited by-同舟云学术

Expression of claudin-8 is induced by aldosterone in renal collecting duct principal cells

Published:2021-11-01 Issue:5 Volume:321 Page:F645-F655
ISSN:1931-857X
Container-title:American Journal of Physiology-Renal Physiology
language:en
Short-container-title:American Journal of Physiology-Renal Physiology

Author:

Sassi Ali¹²^ORCID,Wang Yubao¹²,Chassot Alexandra¹²,Roth Isabelle¹,Ramakrishnan Suresh¹²,Olivier Valérie¹²,Staub Olivier³^ORCID,Udwan Khalil¹,Feraille Eric¹²^ORCID

Affiliation:

1. Department of Cellular Physiology and Metabolism, University of Geneva, Geneva, Switzerland

2. National Center of Competence in Research “Kidney.ch,” Switzerland

3. Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland

Abstract

In this study, we showed that aldosterone modulates claudin-8 expression in cultured collecting duct principal cells and in the mouse kidney. The upregulation of claudin-8 expression in response to aldosterone is dependent on at least glycogen synthase kinase-3, Lyn, and Abl signaling pathways, indicating the participation of multiple protein kinases to the effect of aldosterone.

Funder

SNF | Swiss National Centre of Competence in Research Kidney Control of Homeostasis

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

American Physiological Society

Subject

Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajprenal.00207.2021

Reference40 articles.

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2. Expression of claudin-7 and -8 along the mouse nephron