A plasma creatinine- and urea-based equation to estimate glomerular filtration rate in rats

Author:

Besseling Paul J.1ORCID,Pieters Tobias T.1,Nguyen Isabel T. N.1,de Bree Petra M.1,Willekes Nel1,Dijk Adele H.1,Bovée Dominique M.2,Hoorn Ewout J.2ORCID,Rookmaaker Maarten B.1,Gerritsen Karin G.1,Verhaar Marianne C.1,Gremmels Hendrik13,Joles Jaap A.1ORCID

Affiliation:

1. Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands

2. Division of Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands

3. Department of Medical Microbiology and Immunology, Diakonessenhuis, Utrecht, The Netherlands

Abstract

This is the first equation, that we know of, which estimates glomerular filtration rate in rats based on a single measurement of body weight, plasma creatinine, and plasma urea.

Funder

Hartstichting

Universitair Medisch Centrum Utrecht

ZonMw

Publisher

American Physiological Society

Subject

Physiology

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