Satellite cell and myonuclear accretion is related to training-induced skeletal muscle fiber hypertrophy in young males and females-Reference-Cited by-同舟云学术

Satellite cell and myonuclear accretion is related to training-induced skeletal muscle fiber hypertrophy in young males and females

Published:2021-09-01 Issue:3 Volume:131 Page:871-880
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Abou Sawan Sidney¹,Hodson Nathan¹^ORCID,Babits Paul¹,Malowany Julia M.¹,Kumbhare Dinesh²^ORCID,Moore Daniel R.¹^ORCID

Affiliation:

1. Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada

2. Toronto Rehabilitation Institute, Toronto, Ontario, Canada

Abstract

We demonstrate that training-induced increase in SC content in type II fibers and myonuclear content in type I and II fibers is similar between males and females. Furthermore, these changes are related to the extent of muscle fiber hypertrophy. Thus, SC and myonuclear accretion appear to contribute to muscle hypertrophy irrespective of sex, highlighting the importance of these muscle stem cells in human skeletal muscle growth.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Mitacs

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00424.2021

Reference53 articles.

1. Satellite Cells and Skeletal Muscle Regeneration

2. Satellite cells in human skeletal muscle plasticity