Changes in metabolism and vestibular function depend on gravitational load in mice

Author:

Abe Chikara1ORCID,Katayama Chikako1,Horii Kazuhiro1,Okada Risa2,Kamimura Daisuke2,Nin Fumiaki1,Morita Hironobu1

Affiliation:

1. Department of Physiology, Gifu University Graduate School of Medicine, Gifu, Japan

2. JEM Utilization Center, Human Spaceflight Technology Directorate, Japan Aerospace Exploration Agency (JAXA), Ibaraki, Japan

Abstract

It is unclear whether the degree of change in vestibular-related physiological function depends on gravitational loading. Present study showed that exposure to hypergravity-induced degrees of change in metabolism and vestibular function depended on the gravitational loading. The response of body mass depended on the gravitational loading size. Especially in 2 G environment, water intake, body temperature, and vestibular function were influenced. These changes could involve plastic alteration of vestibular-related autonomic and motor functions.

Funder

Gifu University

MEXT | Japan Aerospace Exploration Agency

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

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