Effects of biological sex and oral contraceptive pill use on cutaneous microvascular endothelial function and nitric oxide-dependent vasodilation in humans-Reference-Cited by-同舟云学术

Effects of biological sex and oral contraceptive pill use on cutaneous microvascular endothelial function and nitric oxide-dependent vasodilation in humans

Published:2023-04-01 Issue:4 Volume:134 Page:858-867
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Turner Casey G.¹^ORCID,Stanhewicz Anna E.²^ORCID,Nielsen Karen E.³,Otis Jeffrey S.¹,Feresin Rafaela G.⁴^ORCID,Wong Brett J.¹^ORCID

Affiliation:

1. Department of Kinesiology and Health, Georgia State University, Atlanta, Georgia, United States

2. Department of Health and Human Physiology, University of Iowa, Iowa City, Iowa, United States

3. Department of Population Health Sciences, School of Public Health, Georgia State University, Atlanta, Georgia, United States

4. Department of Nutrition, Georgia State University, Atlanta, Georgia, United States

Abstract

This study supports differences in microvascular endothelial function and nitric oxide (NO)-dependent vasodilation between women in low hormone phases of two hormonal exposures and men. However, when separated into subgroups of hormonal exposure, women during placebo pills of oral contraceptive pill (OCP) use have greater NO-dependent vasodilation than naturally cycling women in their menstrual phase and men. These data improve knowledge of sex differences and the effect of OCP use on microvascular endothelial function.

Funder

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00586.2022

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