Microvascular Dysfunction in Obesity: A Potential Mechanism in the Pathogenesis of Obesity-Associated Insulin Resistance and Hypertension-Reference-Cited by-同舟云学术

Microvascular Dysfunction in Obesity: A Potential Mechanism in the Pathogenesis of Obesity-Associated Insulin Resistance and Hypertension

Published:2007-08 Issue:4 Volume:22 Page:252-260
ISSN:1548-9213
Container-title:Physiology
language:en
Short-container-title:Physiology

Author:

Jonk Amy M.¹,Houben Alfons J. H. M.¹,de Jongh Renate T.²,Serné Erik H.²,Schaper Nicoloaas C.¹,Stehouwer Coen D. A.¹

Affiliation:

1. Department of Internal Medicine, University Hospital Maastricht, and Cardiovascular Research Institute Maastricht, Maastricht; and

2. Department of Internal Medicine, VU Medical Center, Amsterdam, The Netherlands,

Abstract

Obesity is an important risk factor for insulin resistance and hypertension and plays a central role in the metabolic syndrome. Insight into the pathophysiology of this syndrome may lead to new treatments. This paper has reviewed the evidence for an important role for the microcirculation as a possible link between obesity, insulin resistance and hypertension.

Publisher

American Physiological Society

Subject

Physiology

Link

https://www.physiology.org/doi/pdf/10.1152/physiol.00012.2007

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