Reperfused vs. nonreperfused myocardial infarction: when to use which model-Reference-Cited by-同舟云学术

Reperfused vs. nonreperfused myocardial infarction: when to use which model

Published:2021-07-01 Issue:1 Volume:321 Page:H208-H213
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Lindsey Merry L.¹²^ORCID,de Castro Brás Lisandra E.³,DeLeon-Pennell Kristine Y.⁴⁵^ORCID,Frangogiannis Nikolaos G.⁶,Halade Ganesh V.⁷^ORCID,O’Meara Caitlin C.⁸⁹¹⁰,Spinale Francis G.¹¹,Kassiri Zamaneh¹²,Kirk Jonathan A.¹³^ORCID,Kleinbongard Petra¹⁴^ORCID,Ripplinger Crystal M.¹⁵^ORCID,Brunt Keith R.¹⁶^ORCID

Affiliation:

1. Department of Cellular and Integrative Physiology, Center for Heart and Vascular Research, University of Nebraska Medical Center, Omaha, Nebraska

2. Research Service, Nebraska-Western Iowa Health Care System, Omaha, Nebraska

3. Department of Physiology, The Brody School of Medicine, East Carolina University, Greenville, North Carolina

4. Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina

5. Research Service, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina

6. Department of Medicine (Cardiology), The Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, New York

7. Division of Cardiovascular Sciences, Department of Medicine, University of South Florida, Tampa, Florida

8. Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin

9. Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin

10. Genomics Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, Wisconsin

11. University of South Carolina School of Medicine and Columbia Veteran Affairs HealthCare System, Columbia, South Carolina

12. Department of Physiology, Cardiovascular Research Center, University of Alberta, Edmonton, Alberta, Canada

13. Department of Cell and Molecular Physiology, Loyola University Chicago Stritch School of Medicine, Chicago, Illinois

14. Institute for Pathophysiology, West German Heart and Vascular Center, University of Essen Medical School, Essen, Germany

15. Department of Pharmacology, UC Davis School of Medicine, Davis, California

16. Department of Pharmacology, Faculty of Medicine, Dalhousie University, Saint John, New Brunswick, Canada

Abstract

There is a lack of understanding in the cardiac remodeling field regarding the use of nonreperfused myocardial infarction (MI) and reperfused MI in animal models of MI. This Perspectives summarizes the consensus of the authors regarding how to select the optimum model for your experiments and is a part of ongoing efforts to establish rigor and reproducibility in cardiac physiology research.

Funder

Canadian Institutes of Health Research

HHS | NIH | Office of Extramural Research, National Institutes of Health

U.S. Department of Defense

U.S. Department of Veterans Affairs

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00234.2021

Reference67 articles.