Selective elevation in external carotid artery flow during acute gravitational transition to microgravity during parabolic flight

Author:

Lanéelle Damien12ORCID,Ogoh Shigehiko3ORCID,Trihan Jean-Eudes4ORCID,Bailey Damian M.5ORCID,Normand Hervé16ORCID

Affiliation:

1. INSERM UMRS-1075, COMETE, GIP Cyceron, University of Caen Normandy, Caen, France

2. Department of Vascular Medicine, University Hospital of Caen Normandy, Caen, France

3. Department of Biomedical Engineering, Toyo University, Kawagoe, Japan

4. Unit of Vascular Medicine, Hospital of Cholet, Cholet, France

5. Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Glamorgan, United Kingdom

6. Department of Clinical Physiology, University Hospital of Caen Normandy, Caen, France

Abstract

Our findings demonstrate that in microgravity there is a selective increase in external carotid artery blood flow whereas global and regional cerebral blood flow remained preserved. To what extent this reflects an adaptive, neuroprotective response to counter overperfusion remains to be established.

Funder

French society of vascular medicine

Royal society Wolfson fellowship

Groupe de Coopération Sanitaire interrégional des CHU Amiens

Centre National d'Etudes Spatiales

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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