Cardiovascular risk factors during pregnancy impact the postpartum cardiac and vascular reverse remodeling-Reference-Cited by-同舟云学术

Cardiovascular risk factors during pregnancy impact the postpartum cardiac and vascular reverse remodeling

Published:2023-10-01 Issue:4 Volume:325 Page:H774-H789
ISSN:0363-6135
Container-title:American Journal of Physiology-Heart and Circulatory Physiology
language:en
Short-container-title:American Journal of Physiology-Heart and Circulatory Physiology

Author:

Ferreira Ana Filipa¹^ORCID,Azevedo Maria João²³⁴⁵^ORCID,Morais Juliana¹,Trindade Fábio¹^ORCID,Saraiva Francisca¹^ORCID,Diaz Sílvia Oliveira¹^ORCID,Alves Inês Nuno¹,Fragão-Marques Mariana¹⁶,Sousa Carla¹⁷,Machado Ana Paula⁸,Leite-Moreira Adelino¹⁹,Sampaio-Maia Benedita²³⁴,Ramalho Carla⁸¹⁰^ORCID,Barros António Sousa¹^ORCID,Falcão-Marques Inês¹

Affiliation:

1. Department of Surgery and Physiology, Cardiovascular R&D Centre-UnIC@RISE, Faculdade de Medicina, University of Porto, Porto, Portugal

2. Faculdade de Medicina Dentária, Universidade do Porto, Porto, Portugal

3. INEB–Instituto Nacional de Engenharia Biomédica, Porto, Portugal

4. i3S–Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal

5. Academic Center for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

6. Department of Clinical Pathology, Centro Hospitalar de São João, Porto, Portugal

7. Department of Cardiology, Centro Hospitalar de São João, Porto, Portugal

8. Center of Prenatal Diagnosis, Department of Obstetrics, Centro Hospitalar de São João, Porto, Portugal

9. Department of Cardiothoracic Surgery, Centro Hospitalar de São João, Porto, Portugal

10. Department of Obstetrics, Gynaecology and Pediatrics, Faculty of Medicine, University of Porto, Porto, Portugal

Abstract

This study describes the impact of cardiovascular risk factors (CVR) in pregnancy-induced remodeling and postpartum reverse remodeling (up to 1 yr) by applying advanced statistic methods (multivariate generalized linear mixed-effects models) to a prospective cohort of pregnant women. Aiming to extrapolate to pathological conditions, this invaluable “human model” allowed us to demonstrate that arterial hypertension is a critical CVR for worse RR and that ST2/IL33-receptors and CRP are potential biomarkers of postpartum hypertrophy reversal.

Funder

Portuguese Foundation for Science and Technology

Portugese Foundation for Science and Technology

EC | European Regional Development Fund

Sociedade Portuguesa de Cardiologia

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/ajpheart.00200.2023

Reference68 articles.