Left ventricular remodeling in twin pregnancy, noninvasively assessed using hemodynamic forces and pressure-volume relation analysis: prospective, cohort study

Author:

Pellegrino Alessio12ORCID,Toncelli Loira1ORCID,Pasquini Lucia3ORCID,Masini Giulia3,Mecacci Federico3ORCID,Pedrizzetti Gianni4ORCID,Modesti Pietro Amedeo12ORCID

Affiliation:

1. Sport Medicine Unit, Careggi University Hospital, Florence, Italy

2. Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy

3. Fetal Medicine Unit, Careggi University Hospital, Florence, Italy

4. Department of Engineering and Architecture, University of Trieste, Trieste, Italy

Abstract

These changes indicate that 1) the misalignment of hemodynamic forces (HDFs) precedes a mild reduction in systolic function in twin pregnancy and 2) the positive left ventricular (LV) response to hemodynamic stress is mainly due to an improved diastolic function with enhanced LV cavity compliance.

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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