Affiliation:
1. Department of Medicine and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin
Abstract
We demonstrate that the modulation of p66Shc signaling impairs cerebral artery myogenic tone in a low renin model of hypertension. This impairment is dependent upon the genetic background, as modulated p66Shc signaling in Sprague-Dawley rats does not impair cerebral artery myogenic tone.
Funder
American Heart Association
HHS | NIH | National Heart, Lung, and Blood Institute
Publisher
American Physiological Society
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology
Cited by
4 articles.
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