Novel noninvasive estimation of mixed venous oxygen saturation by echocardiography and expired gas analysis

Author:

Onoue Takeshi1,Iwataki Mai1,Araki Masaru1ORCID,Akashi Jun1,Kitano Tetsuji1ORCID,Nabeshima Yosuke1ORCID,Hei Soshi1ORCID,Nagata Yasufumi1ORCID,Hayashi Atsushi1,Tsuda Yuki1,Sonoda Shinjo1,Fujino Yoshihisa2ORCID,Levine Robert A.3,Otsuji Yutaka1

Affiliation:

1. Second Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan

2. Department of Environmental Epidemiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan

3. Cardiac Ultrasound Laboratory, Massachusetts General Hospital, Boston, Massachusetts

Abstract

Clinical use of mixed venous oxygen saturation ([Formula: see text]) is limited for the required invasive procedure. With Fick’s equation, expired gas analysis, echocardiography, simple blood tests, and percutaneous oxygen saturation, [Formula: see text] can be calculated noninvasively. We hypothesized that noninvasively calculated [Formula: see text] shows a significant correlation and agrees well with invasively measured [Formula: see text]. The present study examined the relationship between measured [Formula: see text] and calculated [Formula: see text] in patients who underwent right heart catheterization and demonstrated acceptable agreement. This novel method can expand the indication of evaluating [Formula: see text].

Funder

the Japan Society of the Promotion of Science KAKENHI

Publisher

American Physiological Society

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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