Changes in Cardiac Output with Age

Author:

BRANDFONBRENER MARTIN1,LANDOWNE MILTON1,SHOCK NATHAN W.1

Affiliation:

1. From the Section on Gerontology, National Heart Institute, National Institutes of Health, U. S. Public Health Service, Department of Health, Education and Welfare, Bethesda and the Baltimore City Hospitals, Baltimore, Md.

Abstract

In the first of two papers, the details and results of a systematic, carefully standardized application of dye dilution technic to the measurement of cardiac output are reported. A substantially reduced output was a consistent finding in older subjects. Factors responsible for this are analyzed in this article, and further interpretations are made in the succeeding article. One result of the analysis of time-concentration curves of dye provides an interesting relationship to clinical estimates of circulation time.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

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