Thiamine Ameliorates Diabetes-Induced Inhibition of Pyruvate Dehydrogenase (PDH) in Rat Heart Mitochondria: Investigating the Discrepancy Between PDH Activity and PDH E1α Phosphorylation in Cardiac Fibroblasts Exposed to High Glucose-Reference-Cited by-同舟云学术

Thiamine Ameliorates Diabetes-Induced Inhibition of Pyruvate Dehydrogenase (PDH) in Rat Heart Mitochondria: Investigating the Discrepancy Between PDH Activity and PDH E1α Phosphorylation in Cardiac Fibroblasts Exposed to High Glucose

Published:2010 Issue:4 Volume:113 Page:343-352
ISSN:1347-8613
Container-title:Journal of Pharmacological Sciences
language:en
Short-container-title:J Pharmacol Sci

Author:

Kohda Yuka,Umeki Masashi,Kono Tatsuji,Terasaki Fumio,Matsumura Hitoshi,Tanaka Takao

Publisher

Japanese Pharmacological Society

Subject

Pharmacology,Molecular Medicine

Reference28 articles.

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3. 3 Bajotto G, Murakami T, Nagasaki M, Tamura T, Tamura N, Harris RA, et al. Downregulation of the skeletal muscle pyruvate dehydrogenase complex in the Otsuka Long-Evans Tokushima Fatty rat both before and after the onset of diabetes mellitus. Life Sci. 2004;75:2117–2130.

4. 4 Schummer CM, Werner U, Tennagels N, Schmoll D, Haschke G, Juretschke HP, et al. Dysregulated pyruvate dehydrogenase complex in Zucker diabetic fatty rats. Am J Physiol Endocrinol Metab. 2008;294:E88–E96.

5. 5 Pilegaard H, Neufer PD. Transcriptional regulation of pyruvate dehydrogenase kinase 4 in skeletal muscle during and after exercise. Proc Nutr Soc. 2004;63:221–226.

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