QT PRODACT: A Multi-site Study of In Vitro Action Potential Assays on 21 Compounds in Isolated Guinea-Pig Papillary Muscles-Reference-Cited by-同舟云学术

QT PRODACT: A Multi-site Study of In Vitro Action Potential Assays on 21 Compounds in Isolated Guinea-Pig Papillary Muscles

Published:2005 Issue:5 Volume:99 Page:423-437
ISSN:1347-8613
Container-title:Journal of Pharmacological Sciences
language:en
Short-container-title:J Pharmacol Sci

Author:

Hayashi Seiji,Kii Yoshihide,Tabo Mitsuyasu,Fukuda Hitoshi,Itoh Tetsuji,Shimosato Takashi,Amano Hideto,Saito Mamoru,Morimoto Hajime,Yamada Kiyoshi,Kanda Atsuhiro,Ishitsuka Toshimasa,Yamazaki Takanobu,Kiuchi Yoichi,Taniguchi Shinya,Mori Tatsuya,Shimizu Shigekazu,Tsurubuchi Yuji,Yasuda Shun-ichi,Kitani Shin-ichi,Shimada Chiaki,Kobayashi Kazuo,Komeno Masaharu,Kasai Chieko,Hombo Toshiyasu,Yamamoto Keiji

Publisher

Japanese Pharmacological Society

Subject

Pharmacology,Molecular Medicine

Reference51 articles.

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2. 2 Haverkamp W, Breithardt G, Camm AJ, Janse MJ, Rosen MR, Antzelevitch C, et al. The potential for QT prolongation and pro-arrhythmia by non-anti-arrhythmic drugs: clinical and regulatory implications. Report on a Policy Conference of the European Society of Cardiology. Cardiovasc Res. 2000;47:219–233.

3. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

4. 5 Guth BD, Germeyer S, Kolb W, Markert M. Developing a strategy for the nonclinical assessment of proarrhythmic risk of pharmaceuticals due to prolonged ventricular repolarization. J Pharmacol Toxicol Methods. 2004;49:159–169.

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