Metformin as a Potential Antitumor Agent
Author:
Affiliation:
1. Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences , University of Kragujevac , Serbia
2. Department of Surgery, Faculty of Medicine Foca , University of East Sarajevo , Foca , Bosnia and Herzegovina
Abstract
Publisher
Walter de Gruyter GmbH
Subject
General Medicine
Link
https://www.sciendo.com/pdf/10.2478/sjecr-2022-0023
Reference105 articles.
1. 1. Schernthaner G, Schernthaner GH. The right place for metformin today. Diabetes Res Clin Pract. 2020;159:107946. doi: 10.1016/j.diabres.2019.107946.31778746
2. 2. Viollet B, Guigas B, Sanz Garcia N, Leclerc J, Foretz M, Andreelli F. Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond). 2012;122(6):253-70.10.1042/CS20110386339886222117616
3. 3. Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J. 2000;348 Pt 3(Pt 3):607-14.10.1042/bj3480607
4. 4. Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 2014;510(7506):542-6.10.1038/nature13270407424424847880
5. 5. Polianskyte-Prause Z, Tolvanen TA, Lindfors S, Dumont V, Van M, Wang H, et al. Metformin increases glucose uptake and acts renoprotectively by reducing SHIP2 activity. FASEB J. 2019;33(2):2858-2869.10.1096/fj.201800529RR633864430321069
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