Investigation of design space for freeze-drying injectable ibuprofen using response surface methodology
Author:
Affiliation:
1. Krka d.d. SI-8000 Novo mesto , Slovenia
2. University of Ljubljana , Faculty of Pharmacy , SI-1000 , Ljubljana , Slovenia
Abstract
Publisher
Walter de Gruyter GmbH
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.sciendo.com/pdf/10.2478/acph-2021-0010
Reference33 articles.
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2. 2. J. Nerurkar, J. W. Beach, M. O. Park and H. W. Jun, Solubility of (±)-ibuprofen and S (+)-ibuprofen in the presence of cosolvents and cyclodextrins, Pharm. Dev. Technol.10 (2005) 413–421; https://doi.org/10.1081/PDT-5444610.1081/PDT-54446
3. 3. K. Stoyanova, Z. Vinarov and S. Tcholakova, Improving ibuprofen solubility by surfactant-facilitated self-assembly into mixed micelles, J. Drug. Deliv. Sci. Tec.36 (2016) 208–215; https://doi.org/10.1016/j.jddst.2016.10.01110.1016/j.jddst.2016.10.011
4. 4. M. Preskar, T. Vrbanec, F. Vrečer, P. Šket, J. Plavec and M. Gašperlin, Solubilization of ibuprofen for freeze dried parenteral dosage forms, Acta Pharm.69 (2019) 17–32; https://doi.org/10.2478/acph-2019-000910.2478/acph-2019-0009
5. 5. K. T. Savjani, A. Gajjar and J. K. Savjani, Drug solubility: Importance and enhancement techniques, ISRN Pharm.12 (2012) Article ID 195727; http://dx.doi.org/10.5402/2012/19572710.5402/2012/195727
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