Energy-Related Hormones in Raw and Retail Cow’s Milk and Possible Risk for Consumers
Author:
Knežević Dragan1, Bošnjaković Dušan2, Dražić Slavica2, Nedić Sreten3, Vujanac Ivan3, Valčić Olivera2, Pantelić Marija4, Stojiljković Mojca4, Sladojević Željko1, Kirovski Danijela2
Affiliation:
1. PI Veterinary Institute of the Republic of Srpska Dr Vaso Butozan , Branka Radičevića 18 , Banja Luka , Bosnia and Herzegovina 2. University of Belgrade, Faculty of Veterinary Medicine , Department of Physiology and Biochemistry , Bul. Oslobodjenja 18 , Belgrade , Serbia 3. University of Belgrade, Faculty of Veterinary Medicine, Department of Ruminant and Swine Diseases , Bul. Oslobodjenja 18 , Belgrade , Serbia 4. Vinča Institute of Nuclear Science , University of Belgrade, National Institute of the Republic of Serbia , Laboratory for Molecular Biology and Endocrinology, Mike Petrovića Alasa 12-14 , Belgrade , Serbia
Abstract
Abstract
The study aimed to determine the concentration of energy-related hormones in cow’s milk and to consider them from a public health perspective. Fourteen Holstein cows were subjected to milk and blood sampling on the following days in lactation (DIL): 10, 30, 60, 90, 150, 180, 210, 250 and 280 to determine milk hormones, fat and protein content and blood biochemical parameters. For the same purpose, bulk-tank milk was sampled and samples of retail m ilk with 1.5% (CM1.5) and 3.2% (CM3.2) fat was purchased. Milk insulin-like growth factor-1 (IGF-1) values were significantly lower at 90, 150, 180, 210 and 250 and significantly higher at 10, 30 and 60 DIL than lactation average (LA). Milk insulin concentrations were significantly lower at 30, 60 and 90 and higher at 210, 250 and 280 DIL than LA. Free thyroxine (fT4) level in the milk was higher at 250 DIL, while milk free triiodothyronine (fT3) concentrations were lower at 30, 60, 90 and 280 DIL, and significantly higher at 10 and 180 DIL than respective LA. Milk cortisol levels were lower at 60 and 280 DIL than LA. All measured milk hormones were significantly lower in CM1.5 compared to CM3.2, bulk-tank milk and LA. An exception was the LA of IGF-1, which was significantly lower than the IGF-1 content in CM1.5. Blood biochemical parameters fluctuated evenly during lactation and were within the reference range. Hormone concentrations in cow’s milk fluctuate during lactation, giving milk an important role in the context of public health.
Publisher
Walter de Gruyter GmbH
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