Transcranial Duplex Ultrasonography Measurements Towards Identification of Blood Vessel Conditions: Artificial Cerebral Blood Flow in Pathologies

Author:

Leibuss Roberts12,Posredņikova Olga3,Pupkeviča Irina12,Meidrops Kristiāns12,Mackevičs Dāvis4,Dekhtyar Yuri3,Stradiņš Pēteris12,Strīķe Eva12

Affiliation:

1. Cardiac Surgery Centre , Pauls Stradiņš Clinical University Hospital , 13 Pilsoņu Str ., Rīga , , Latvia

2. Faculty of Medicine , Rīga Stradiņš University , 16 Dzirciema Str ., Rīga , , Latvia

3. Institute of Biomedical Engineering and Nanotechnologies , Rīga Technical University , 6B Ķīpsalas Str ., Rīga , , Latvia

4. Faculty of Medicine , University of Latvia , 19 Raiņa Blvd , Rīga , , Latvia

Abstract

Abstract The aim of the study was to investigate how cerebral vasospasm, vasodilation and haemorrhage under artificial circulation conditions during cardiopulmonary bypass affect transcranial duplex ultrasonography measurements. A description of transcranial duplex ultrasonography and phantom development is provided. Measurements were made using a commercially available ultrasound system and cardiopulmonary bypass machine, water phantom and 32% glycerol solution with cornstarch. The experiments showed that the cerebral blood vessel condition in artificial circulation affects transcranial duplex ultrasonography measurement limit values. The most sensitive parameter for blood vessel condition changes is Peak Systolic Velocity (PSV) for which changes were observed in 100% of cases. The most insensitive was Time-Averaged Peak-Velocity (TAPV), and Minimum Diastolic Velocity (MDV) for which changes were observed in 83% of cases.

Publisher

Walter de Gruyter GmbH

Reference19 articles.

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