Effects of an Exogenous Ketone Supplement on Five‐Kilometer Running Performance
Author:
Prins Philip J.1, Koutnik Andrew P.2, D’Agostino Dominic P.2, Rogers Christopher Q.2, Seibert Jacob F.1, Breckenridge Jillian A.1, Jackson Daniel S.1, Ryan Edward J.3, Buxton Jeffrey D.1, Ault Dana L.1
Affiliation:
1. Department of Exercise Science, Grove City College , Grove City, PA , USA 2. Department of Molecular Pharmacology & Physiology, University of South Florida , South Florida , USA 3. Department of Exercise Science, Chatham University , Pittsburgh, PA , USA
Abstract
Abstract
Numerous oral ketone supplements are marketed with the claim that they will rapidly induce ketosis and improve exercise performance. The purpose of this study was to assess exercise performance time and related physiological, metabolic and perceptual responses of recreational endurance runners after ingestion of a commercially available oral ketone supplement. Recreational endurance runners (n = 10; age: 20.8 ± 1.0 years; body mass: 68.9 ± 5.6 kg; height: 175.6 ± 4.9 cm) participated in a double-blind, crossover, repeated-measures study where they were randomized to 300 mg.kg-1 body weight of an oral β-hydroxybutyrate-salt + Medium Chain Triglyceride (βHB-salt+MCT) ketone supplement or a flavor matched placebo (PLA) 60 min prior to performing a 5-km running time trial (5KTT) on a treadmill. Time, HR, RPE, affect, RER, VO2, VCO2, and VE were measured during the 5-km run. The Session RPE and affect (Feeling Scale) were obtained post-5KTT. Plasma glucose, lactate and ketones were measured at baseline, 60-min post-supplement, and immediately post-5KTT. Plasma R-βHB (endogenous isomer) was elevated from baseline and throughout the entire protocol under the βHB-salt+MCT condition (p < 0.05). No significant difference (58.3 ± 100.40 s; 95% CI: -130.12 – 13.52; p = 0.100) was observed between the βHB-salt+MCT supplement (1430.0 ± 187.7 s) and the PLA (1488.3 ± 243.8 s) in time to complete the 5KTT. No other differences (p > 0.05) were noted in any of the other physiological, metabolic or perceptual measures.
Publisher
Walter de Gruyter GmbH
Subject
Physiology (medical),Physical Therapy, Sports Therapy and Rehabilitation
Reference41 articles.
1. Astorino TA, Matera AJ, Basinger J, Evans M, Schurman T, Marquez R. Effects of red bull energy drink on repeated sprint performance in women athletes. Amino Acids, 2012; 42: 1803-1808 2. Bach AC, Ingenbleek Y, Frey A. The usefulness of dietary medium-chain triglycerides in body weight control: fact or fancy? J Lipid Res, 1996; 37: 708-726 3. Cahill GF, Jr. Fuel metabolism in starvation. Annu Rev Nutr, 2006; 26: 1-22 4. Cox PJ, Kirk T, Ashmore T, Willerton K, Evans R, Smith A, Murray AJ, Stubbs B, West J, McLure SW, King MT, Dodd MS, Holloway C, Neubauer S, Drawer S, Veech RL, Griffin JL, Clarke K. Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes. Cell Metab, 2016; 24: 256-268 5. Dansinger ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ. Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial. JAMA, 2005; 293: 43-53
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