Nosocomial infectious complications in patients with urological malignancies-Reference-Cited by-同舟云学术

Nosocomial infectious complications in patients with urological malignancies

Published:2021-05-06 Issue:1 Volume:17 Page:126-133
ISSN:1996-1812
Container-title:Cancer Urology
language:
Short-container-title:Onkourologiâ

Author:

Dmitrieva N. V.¹,Aginova V. V.²^ORCID,Petukhova I. N.¹^ORCID,Sokolova E. N.¹,Dyakova S. A.¹,Grigoryevskaya Z. V.¹^ORCID,Kulaga E. N.¹

Affiliation:

1. N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

2. Medical College No. 1

Abstract

The objective of the study was to analyze the taxonomic structure of urinary infection pathogens and determine the susceptibility of ESKAPE group microorganisms (Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Enterococcus spp.) isolated from cancer patients with nosocomial infections in 2018—2020 to antimicrobials.Materials and methods. 413 (71.9 %) strains of ESKAPE group bacteria from 228 patients were studied. Microorganisms were identified and antibiotic resistance was determined using Vitek-2 System (France) and MicroScan WalkAway (Germany / USA) analyzers.Results and conclusion. All gram-positive microorganisms were highly sensitive to vancomycin and teicoplanin, linezolid, tigecycline, and daptomycin, which can be used in the treatment if clinical indications are seen. Among gram-negative bacteria, the percentage of ESBL producers was 60—70 %, the percentage of carbapenem-resistant bacteria was minimalfor E. coli, rnmpared to the rest - 40—50 %, demonstrating the need to limit the use of carbapenems in the clinic.

Publisher

Publishing House ABV Press

Subject

Urology,Nephrology,Radiology Nuclear Medicine and imaging,Oncology,Surgery

Reference12 articles.

1. Petukhova I.N., Sokolovsky A.V., Grigo-rievskaya Z.V. et al. Infections associated with the installation of foreign materials (prostheses, meshes, implants). Zlokachestvennye opukholi = Malignant Tumors 2017;(3s1):57-60. (In Russ.). DOI: 10.18027/2224-5057-2017-3s1-57-60.

2. Mulvey M.A., Klumpp D.J., Stapleton A.E. Urinary tract infections: molecular pathogenesis and clinical management. 2nd edn. 2017. 675 p.

3. Tancheva S., Micheva I., Marinova I. et al. Infections in urinary tract of patients with haematological malignancies undergoing antineoplastic therapy. J IMAB-Ann Proc (Sci Papers) 2009;15(3):95-7. DOI: 10.5272/jimab.1512009_95.

4. Dmitrieva N.V., Eidelstein M.V., Aginova V.V. et al. Pseudomonas aeruginosa nosocomial infections in a cancer clinic. Sibirskiy onkologicheskiy zhurnal = Siberian Journal of Oncology 2019;18(2):28-34. (In Russ.). DOI: 10.21294/1814-4861-2019-18-2-28-34.

5. Zemlyanko O.M., Rogoza T.M., Zhuravleva G.A. Mechanisms of multiple bacterial resistance to antibiotics. Ekologicheskaya genetika = Ecological Genetics 2018;16(3):4-17. (In Russ.). DOI: 10.17816/ecogen1634-17.