Affiliation:
1. A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia
Abstract
Sarcomas are common among a rare and heterogeneous group of solid tumors of mesenchymal origin, accounting for only 1 % of all adult malignancies. Soft tissue sarcoma arises primarily from the embryonic mesoderm with some involvement of the neuroectoderm. The modern World Health Organization clinical and morphological classification includes more than 100 forms of these tumors. The diagnostic methods and treatment modalities of soft tissue sarcomas have evolved with the multidisciplinary approach. The standard treatment for localized phase sarcomas is local excision followed by radiotherapy, but since 2010 preoperative radiotherapy has been considered the preferred option (according to the recommendations of the National Comprehensive Cancer Network, NCCN). The use of vascular surgery and femoropopliteal autovenous grafting in surgical tactics allows performing radical operations with limb preservation. The article presents a clinical case of treatment of a patient with a diagnosis of soft tissue leiomyosarcoma of the right popliteal region. In the volume of combined treatment, the surgical intervention – removal of a soft tissue tumor low part of the right thigh and popliteal fossa with resection of the posterior thigh muscle group together with the involved popliteal artery, with simultaneous femoropopliteal autovenous prosthetics – was performed.
Publisher
Publishing House ABV Press
Reference17 articles.
1. Von Mehren M., Kane J.M., Agulnik M. et al. Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 2022;20(7):815–33. DOI: 10.6004/jnccn.2022.0035
2. Benberin V.V., Baizakov B.T.,. Shanazarov N.A., Zinchenko S.V. Soft tissue sarcomas: a modern view of the problem. Vestnik Avicenny = Avicenna Bulletin 2019;21(2):291–7. (In Russ.). DOI: 10.25005.2074-0581-2019-21-2-291-297
3. Zubarev A.L., Kurilchik A.A., Kurpeshev O.K. et al. local hyperthermia in the combined treatment of locally advanced soft tissue sarcomas. Sibirskij onkologicheskij zhurnal = Siberian Journal of Oncology 2015;1(3):55–60. (In Russ.).
4. Atlas of tumor pathology. 3 Series. Fascicle 30. Tumors of the soft tissues. Bethesda, Maryland, 2001. Pp. 1–420.
5. Fletcher C.D.M., Unni K.K., Mertens F. Pathology and genetics of tumors of soft tissue and bone. WHO Classification of Tumours. Ed. by C.D.M. Fletcher, K.K. Unni, F. Mertens. 3rd edn. Vol. 5. Lyon, France: IARC Press, 2002. Р. 70.