Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology

Author:

von Mehren Margaret1,Kane John M.2,Agulnik Mark3,Bui Marilyn M.4,Carr-Ascher Janai5,Choy Edwin6,Connelly Mary7,Dry Sarah8,Ganjoo Kristen N.9,Gonzalez Ricardo J.4,Holder Ashley10,Homsi Jade11,Keedy Vicki12,Kelly Ciara M.13,Kim Edward14,Liebner David7,McCarter Martin15,McGarry Sean V.16,Mesko Nathan W.17,Meyer Christian18,Pappo Alberto S.19,Parkes Amanda M.20,Petersen Ivy A.21,Pollack Seth M.22,Poppe Matthew23,Riedel Richard F.24,Schuetze Scott25,Shabason Jacob26,Sicklick Jason K.27,Spraker Matthew B.28,Zimel Melissa29,Hang Lisa E.30,Sundar Hema30,Bergman Mary Anne30

Affiliation:

1. 1Fox Chase Cancer Center;

2. 2Roswell Park Comprehensive Cancer Center;

3. 3City of Hope National Medical Center;

4. 4Moffitt Cancer Center;

5. 5UC Davis Comprehensive Cancer Center;

6. 6Massachusetts General Hospital Cancer Center;

7. 7The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute;

8. 8UCLA Jonsson Comprehensive Cancer Center;

9. 9Stanford Cancer Institute;

10. 10O'Neal Comprehensive Cancer Center at UAB;

11. 11UT Southwestern Simmons Comprehensive Cancer Center;

12. 12Vanderbilt-Ingram Cancer Center;

13. 13Memorial Sloan Kettering Cancer Center;

14. 14Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance;

15. 15University of Colorado Cancer Center;

16. 16Fred & Pamela Buffett Cancer Center;

17. 17Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute;

18. 18The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;

19. 19St. Jude Children’s Research Hospital/The University of Tennessee Health Science Center;

20. 20University of Wisconsin Carbone Cancer Center;

21. 21Mayo Clinic Cancer Center;

22. 22Robert H. Lurie Comprehensive Cancer Center of Northwestern University;

23. 23Huntsman Cancer Institute at the University of Utah;

24. 24Duke Cancer Institute;

25. 25University of Michigan Rogel Cancer Center;

26. 26Abramson Cancer Center at the University of Pennsylvania;

27. 27UC San Diego Moores Cancer Center;

28. 28Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine;

29. 29UCSF Helen Diller Family Comprehensive Cancer Center; and

30. 30National Comprehensive Cancer Network.

Abstract

Soft tissue sarcomas (STS) are rare malignancies of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Soft Tissue Sarcoma provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial trunk/head and neck STS, as well as retroperitoneal/intra-abdominal STS, desmoid tumors, and rhabdomyosarcoma. This portion of the NCCN Guidelines discusses general principles for the diagnosis and treatment of retroperitoneal/intra-abdominal STS, outlines treatment recommendations, and reviews the evidence to support the guidelines recommendations.

Publisher

Harborside Press, LLC

Subject

Oncology

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