Serum β-hexosaminidase isoenzymes are precursor forms

Author:

Isaksson A.,Hultberg B.

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,General Medicine

Reference23 articles.

1. Skudlarek M D, Novak E K, Swank R T. Processing of lysosomal enzymes in macrophages and kidney. In: Dingle IT, Dean RT, Sly WS, editors. Lysosomes in biology and pathology. Elsevier, Amsterdam 1984; vol 7, 63–82

2. Creek K E, Sly W S. The role of phosphomannosyl receptor in the transport of acid hydrolases to lysosomes. In: Dingle IT, Dean RT, Sly WS, editors. Lysosomes in biology and pathology. Elsevier, Amsterdam 1984; vol 7, 63–82

3. Natural History and Inherited Disorders of a Lysosomal Enzyme, β-Hexosaminidase

4. The amino-terminal sequences in the pro-α and -β polypeptides of human lysosomal β-hexosaminidase A and B are retained in the mature isozymes

5. Proteolytic processing of the alpha-chain of the lysosomal enzyme, beta-hexosaminidase, in normal human fibroblasts.

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