Synthesis and evaluation of biological and antitumor activities of 5,7-dimethyl- oxazolo[5,4-d]pyrimidine-4,6(5H,7H)-dione derivatives as novel inhibitors of FGFR1-Reference-Cited by-同舟云学术

Synthesis and evaluation of biological and antitumor activities of 5,7-dimethyl- oxazolo[5,4-d]pyrimidine-4,6(5H,7H)-dione derivatives as novel inhibitors of FGFR1

Published:2015-02-16 Issue:6 Volume:30 Page:961-966
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Ye Faqing¹²,Wang Yuewu²,Nian Siyun²,Wang Yu²,Chen Di²,Yu Shufang²,Wang Sicen¹

Affiliation:

1. School of Pharmacy, Health Science Center Xi’an Jiaotong University, Xi’an, China and

2. School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.3109/14756366.2014.1002401

Reference25 articles.

1. Effect of inhibition of the FGFR–MAPK signaling pathway on the development of ocular toxicities

2. Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

3. Receptor Tyrosine Kinases and Targeted Cancer Therapeutics

4. FGF-2 Regulates Cell Proliferation, Migration, and Angiogenesis through an NDY1/KDM2B-miR-101-EZH2 Pathway

5. Fibroblast growth factor signalling: from development to cancer

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