Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase-Reference-Cited by-同舟云学术

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

Published:2011-09-21 Issue:20 Volume:54 Page:7066-7083
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Guagnano Vito¹,Furet Pascal¹,Spanka Carsten¹,Bordas Vincent¹,Le Douget Mickaël¹,Stamm Christelle¹,Brueggen Josef¹,Jensen Michael R.¹,Schnell Christian¹,Schmid Herbert¹,Wartmann Markus¹,Berghausen Joerg¹,Drueckes Peter¹,Zimmerlin Alfred¹,Bussiere Dirksen¹,Murray Jeremy¹,Graus Porta Diana¹

Affiliation:

1. Novartis Institute for BioMedical Research, CH-4002 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2006222

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