Design, synthesis, and evaluation of guanylhydrazones as potential inhibitors or reactivators of acetylcholinesterase-Reference-Cited by-同舟云学术

Design, synthesis, and evaluation of guanylhydrazones as potential inhibitors or reactivators of acetylcholinesterase

Published:2015-11-11 Issue:6 Volume:31 Page:1069-1078
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Petronilho Elaine da Conceição¹,Rennó Magdalena do Nascimento²,Castro Newton Gonçalves³,da Silva Fernanda Motta R.³,Pinto Angelo da Cunha¹,Figueroa-Villar José Daniel¹

Affiliation:

1. Department of Chemistry, Military Institute of Engineering, Rio De Janeiro, Brazil,

2. Laboratory of Molecular Modeling and Pharmaceutical Sciences, Federal University of Rio De Janeiro, Macaé, Brazil, and,

3. Institute of Biomedical Sciences, Federal University of Rio De Janeiro, Rio De Janeiro, Brazil

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.3109/14756366.2015.1094468

Reference36 articles.

1. Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase

2. The Cholinesterases: From Genes to Proteins

3. Testing of novel brain-penetrating oxime reactivators of acetylcholinesterase inhibited by nerve agent surrogates

4. Organophosphorus compounds as chemical warfare agents: a review

5. Molecular dynamics simulations and QM/MM studies of the reactivation by 2-PAM of tabun inhibited human acethylcolinesterase

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