Role of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats-Reference-Cited by-同舟云学术

Role of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats

Published:2014-06-20 Issue:12 Volume:44 Page:1108-1116
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Subramanian Murali,Kurawattimath Vishwanath,Pocha Krishna,Freeden Chris,Rao Indranil,Thanga Mariappan T.,Marathe Punit H.,Vikramadithyan Reeba K.,Abraham Pamela,Kulkarni Chetan P.,Katnapally Prasanna,Nutakki Ravikumar,Paruchury Sundeep,Bhutani Priyadeep,Mandlekar Sandhya

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498254.2014.932470

Reference46 articles.

1. Phenytoin Disposition in Obesity

2. Prolonged Accumulation of Diazepam in Obesity

3. Diazepam metabolism by human liver microsomes is mediated by both S- mephenytoin hydroxylase and CYP3A isoforms.

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