Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes viain vivoandin vitrooxidation of midazolam and triazolam-Reference-Cited by-同舟云学术

Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes viain vivoandin vitrooxidation of midazolam and triazolam

Published:2013-01-03 Issue:7 Volume:43 Page:598-606
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Kuze J.,Mutoh T.,Takenaka T.,Oda N.,Hanioka N.,Narimatsu S.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498254.2012.751517

Reference36 articles.

1. Naringin is a Major and Selective Clinical Inhibitor of Organic Anion-Transporting Polypeptide 1A2 (OATP1A2) in Grapefruit Juice

2. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

4. Human Extrahepatic Cytochromes P450: Function in Xenobiotic Metabolism and Tissue-Selective Chemical Toxicity in the Respiratory and Gastrointestinal Tracts

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