Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepatocytes-Reference-Cited by-同舟云学术

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Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepatocytes

Published:2013-05-08 Issue:11 Volume:43 Page:956-962
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Tanoue Chiaki,Sugihara Kazumi,Uramaru Naoto,Tayama Yoshitaka,Watanabe Yoko,Horie Toru,Ohta Shigeru,Kitamura Shigeyuki

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498254.2013.788232

Reference41 articles.

1. Characterization of Humanized Liver from Chimeric Mice Using Coumarin as a Human CYP2A6 and Mouse CYP2A5 Probe

2. Molybdenum Hydroxylases as Drug-Metabolizing Enzymes

3. A Placebo-Controlled Evaluation of Single, Escalating Doses of CL 284,846, a Non-Benzodiazepine Hypnotic

4. Mammalian molybdo-flavoenzymes, an expanding family of proteins: structure, genetics, regulation, function and pathophysiology

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1. Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css–MRTpo method and chimeric mice with humanised livers;Xenobiotica;2023-09-02

2. Physiologically Based Pharmacokinetic Modeling for Quantitative Prediction of Exposure to a Human Disproportionate Metabolite of the Selective Na_V1.7 Inhibitor DS-1971a, a Mixed Substrate of Cytochrome P450 and Aldehyde Oxidase, Using Chimeric Mice With Humanized Liver;Drug Metabolism and Disposition;2022-10-23

3. Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver;Cell & Bioscience;2022-03-07

4. Oxidative metabolism and pharmacokinetics of the EGFR inhibitor BIBX1382 in chimeric NOG-TKm30 mice transplanted with human hepatocytes;Drug Metabolism and Pharmacokinetics;2021-12

5. Aldehyde oxidase; new approaches to old problems;Xenobiotica;2019-06-19

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