Evaluation of a chimeric (uPA+/+)/SCID mouse model with a humanized liver for prediction of human metabolism-Reference-Cited by-同舟云学术

Evaluation of a chimeric (uPA+/+)/SCID mouse model with a humanized liver for prediction of human metabolism

Published:2011-03-04 Issue:6 Volume:41 Page:464-475
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Serres Mark De,Bowers Gary,Boyle Gary,Beaumont Claire,Castellino Steve,Sigafoos James,Dave Mehul,Roberts Andrew,Shah Vishal,Olson Katie,Patel Dipak,Wagner David,Yeager Russell,Serabjit-Singh Cosette

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.3109/00498254.2011.560295

Reference22 articles.

1. Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice

2. Assessment of Cryopreserved Hepatocytes as an Alternative to Fresh Hepatocytes forComparative InterspeciesMetabolism Studieswith Suitable Acceptance Criteria

3. Evaluation of preparative high performance liquid chromatography and cryoprobe-nuclear magnetic resonance spectroscopy for the early quantitative estimation of drug metabolites in human plasma

4. The disposition and metabolism of GW695634: A non-nucleoside reverse transcriptase inhibitor (NNRTi) for treatment of HIV/AIDS

5. Present and future in vitro approaches for drug metabolism

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