Continuous Flow Synthesis of Dimethylalkynylaluminum Reagents-Reference-Cited by-同舟云学术

Continuous Flow Synthesis of Dimethylalkynylaluminum Reagents

Published:2016-07-07 Issue:19 Volume:48 Page:3272-3278
ISSN:0039-7881
Container-title:Synthesis
language:en
Short-container-title:Synthesis

Author:

Piccardi Riccardo¹,Coffinet Anais¹,Benedetti Erica¹,Turcaud Serge¹,Micouin Laurent¹

Affiliation:

1. Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601 CNRS-Université Paris Descartes, Faculté des Sciences Fondamentales et Biomédicales

Abstract

A new process for the synthesis of dimethylalkynylaluminum reagents under flow conditions is described. It involves a base-catalyzed alumination of terminal alkynes using a resin-supported organocatalyst. Final organometallic species are obtained in solution, and can further react with various aldehydes or nitrones.

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0035-1561484.pdf

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