Update Breast Cancer 2020 Part 1 – Early Breast Cancer: Consolidation of Knowledge About Known Therapies-Reference-Cited by-同舟云学术

Update Breast Cancer 2020 Part 1 – Early Breast Cancer: Consolidation of Knowledge About Known Therapies

Published:2020-03 Issue:03 Volume:80 Page:277-287
ISSN:0016-5751
Container-title:Geburtshilfe und Frauenheilkunde
language:de
Short-container-title:Geburtshilfe Frauenheilkd

Author:

Schneeweiss Andreas¹,Hartkopf Andreas D.²,Müller Volkmar³,Wöckel Achim⁴,Lux Michael P.⁵,Janni Wolfgang⁶,Ettl Johannes⁷,Belleville Erik⁸,Huober Jens⁶,Thill Marc⁹,Fasching Peter A.¹⁰,Kolberg Hans-Christian¹¹,Pöschke Patrik¹⁰,Welslau Manfred¹²,Overkamp Friedrich¹³,Tesch Hans¹⁴,Fehm Tanja N.¹⁵,Lüftner Diana¹⁶,Schütz Florian¹⁷

Affiliation:

1. National Center for Tumor Diseases, Division Gynecologic Oncology, University Hospital and German Cancer Research Center, Heidelberg, Germany

2. Department of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany

3. Department of Gynecology, Hamburg-Eppendorf University Medical Center, Hamburg, Germany

4. Department of Gynecology and Obstetrics, University Hospital Würzburg, Würzburg, Germany

5. Klinik für Gynäkologie und Geburtshilfe, Frauenklinik St. Louise, Paderborn, St. Josefs-Krankenhaus, Salzkotten, Germany

6. Department of Gynecology and Obstetrics, Ulm University Hospital, Ulm, Germany

7. Department of Obstetrics and Gynecology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

8. ClinSol GmbH & Co KG, Würzburg, Germany

9. Agaplesion Markus Krankenhaus, Frauenklinik, Frankfurt, Germany

10. Erlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany

11. Department of Gynecology and Obstetrics, Marienhospital Bottrop, Bottrop, Germany

12. Onkologie Aschaffenburg, Aschaffenburg, Germany

13. OncoConsult Overkamp GmbH, Berlin, Germany

14. Oncology Practice at Bethanien Hospital Frankfurt, Frankfurt, Germany

15. Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Düsseldorf, Germany

16. Charité University Hospital, Campus Benjamin Franklin, Department of Hematology, Oncology and Tumour Immunology, Berlin, Germany

17. Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany

Abstract

AbstractThis review is intended to present the latest developments in the prevention and treatment of early breast cancer. The risk of breast cancer can be increasingly better characterised with large epidemiological studies on genetic and non-genetic risk factors. Through new analyses, the evidence for high-penetrance genes as well as for low-penetrance genes was able to be improved. New data on denosumab and atezolizumab are available in the neoadjuvant situation as is a pooled appraisal of numerous studies on capecitabine in the curative situation. There is also an update to the overall survival data of pertuzumab in the adjuvant situation with a longer follow-up observation period. Finally, digital medicine is steadily finding its way into science. A recently conducted study on automated breast cancer detection using artificial intelligence establishes the basis for a future review in clinical studies.

Publisher

Georg Thieme Verlag KG

Subject

Maternity and Midwifery,Obstetrics and Gynecology

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1111-2431.pdf

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