A Diastereoselective Synthetic Approach towards the Synthesis of Berkeleylactone F and Its 4-epi-Derivative

Author:

Saha Sumit1ORCID,Subba Srijana1,Mandal Susanta2

Affiliation:

1. Department of Chemistry, National Institute of Technology Sikkim

2. Department of Chemistry, Sikkim University

Abstract

AbstractA diastereoselective approach to the synthesis of berkeleylactone F is presented. The synthetic strategy is initiated with commercially available (R)-glycidol, 1,6-heptadiyne, and (R)-(+)-methyl lactate. The key feature of the approach is directional functionalization at both terminals of 1,6-heptadiyne.

Funder

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Materials Science (miscellaneous),Biomaterials,Catalysis

Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. First total synthesis of aspergillolide;Tetrahedron Letters;2022-09

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3. Synthesis and structure–activity relationship of berkeleylactone A-derived antibiotics;Organic & Biomolecular Chemistry;2022

4. Total synthesis of Berkeleylactone F;Synthetic Communications;2021-12-07

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