Staging Severity of COVID-19 according to Hemostatic Abnormalities (CAHA Score)

Author:

Marchandot Benjamin1,Trimaille Antonin1,Curtiaud Anaïs1,Carmona Adrien1,Matsushita Kensuke12ORCID,Sato Chisato12,Leonard-Lorant Ian3,Sattler Laurent4,Grunebaum Lelia4,Ohana Mickaël3,Ohlmann Patrick1,Jesel Laurence12,Morel Olivier12

Affiliation:

1. Division of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France

2. INSERM (French National Institute of Health and Medical Research), Regenerative Nanomedicine, FMTS, Strasbourg, France

3. Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France

4. Department Laboratory Haematology, Centre for Thrombosis and Haemostasis, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France

Abstract

AbstractThis is the first study to show a stepwise increase in venous thrombotic events according to COVID-19 coagulopathy (COVID-19-associated hemostatic abnormalities [CAHA]) staging and lung injuries assessed by chest computed tomography. Excess mortality and/or transfer to intensive care unit according to CAHA staging.

Publisher

Georg Thieme Verlag KG

Subject

Hematology

Reference14 articles.

1. Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to D-dimer levels;I Leonard-Lorant;Radiology,2020

2. COVID-19-related severe hypercoagulability in patients admitted to intensive care unit for acute respiratory failure;L Spiezia;Thromb Haemost,2020

3. Prevention and treatment of venous thromboembolism associated with coronavirus disease 2019 infection: a consensus statement before guidelines;Z Zhai;Thromb Haemost,2020

4. Hypercoagulation and antithrombotic treatment in coronavirus 2019: a new challenge;F Violi;Thromb Haemost,2020

5. A proposal for staging COVID-19 coagulopathy;J Thachil;Res Pract Thromb Haemost,2020

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