Room-Temperature Palladium(II)-Catalyzed Direct 2-Arylation of Indoles with Tetraarylstannanes-Reference-Cited by-同舟云学术

Room-Temperature Palladium(II)-Catalyzed Direct 2-Arylation of Indoles with Tetraarylstannanes

Published:2020-08-05 Issue:16 Volume:31 Page:1613-1618
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Liu Yuxia¹,Xue Dong²,Wang Chao²,Huang Linjuan¹

Affiliation:

1. Shaanxi Natural Carbohydrate Resource Engineering Research Center, College of Food Science and Technology, Northwest University

2. Key Laboratory of Applied Surface and Colloid Chemistry, Ministry of Education and School of Chemistry and Chemical Engineering, Shaanxi Normal University

Abstract

A palladium(II)-catalyzed direct 2-arylation of indoles by tetraarylstannanes with oxygen (balloon) as the oxidant at room temperature has been developed. Various tetraarylstannanes can be employed as aryl sources for 2-arylation of indoles in up to 89% yield, providing a practical and efficient catalytic protocol for accessing 2-arylindoles.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0040-1707196.pdf

Reference16 articles.

1. Pd(OAc)2-Catalyzed Regioselective Arylation of Indoles with Arylsiloxane in Acidic Medium

2. Palladium-Catalyzed Direct and Site-Selective Desulfitative Arylation of Indoles with Sodium Sulfinates