Affiliation:
1. Guizhou Minzu University
2. State Key Lab of Urban Water Resource and Environment School of Science Harbin Institute of Technology (Shenzhen)
3. College of Education for the Future & College of Arts and Sciences, Beijing Normal University
Abstract
AbstractHerein, we report a regioselective cycloaddition strategy of N-aminopyridinium ylides with electron-deficient alkenes, in the presence of a hypervalent iodine reagent, PhI(OAc)2. A variety of multifunctionalized pyrazolo[1,5-a]pyridine architectures were smoothly afforded by the reactions of pyridine-, quinoline-, and isoquinoline-based N-ylides with diverse alkenes with or without a halogen atom adjacent to the electron-withdrawing group (EWG) under facile conditions.
Funder
Science and Technology Project of Guizhou Province
Youth talent growth project of Department of Education of Guizhou Province
Innovation Team Project of Guizhou Higher Education
Science and Technology Project of Guizhou Minzu University