Affiliation:
1. Dipartimento di Chimica, Università degli Studi di Milano
2. Chemistry Department, Espírito Santo Federal University
Abstract
AbstractThis review summarizes the latest developments in asymmetric domino reactions, with the emphasis on the preparation of spiro compounds. Discussions on the stereoselectivity of the transformations, the reaction mechanisms, the rationalization of the stereochemical outcome, and the applications of domino reactions to the synthesis of biologically active molecules and natural products are included when appropriate.1 Introduction2 Asymmetric Domino Reactions2.1 Domino Reactions Initiated by Michael Reactions2.2 Domino Reactions Initiated by Mannich Reactions2.3 Domino Reactions Initiated by Knoevenagel Reactions2.4 Domino Reactions Initiated by Cycloaddition Reactions2.5 Domino Reactions Initiated by Metal Insertion2.6 Other Mechanisms3 Conclusion
Funder
Ministero dell’Istruzione, dell’Università e della Ricerca
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Subject
Organic Chemistry,Catalysis
Cited by
25 articles.
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