Affiliation:
1. College of Pharmacy and Biological Engineering, Chengdu University
2. College of Chemistry and Chemical Engineering, China West Normal University
Abstract
A three-component reaction of β,γ-unsaturated α-keto esters, proline, and dialkyl maleates has been developed. This reaction provides pyrrolizidine derivatives containing three ester groups and a styrenyl group, as well as a quaternary center, in moderate to good yields and with good to excellent diastereoselectivities.
Funder
National Natural Science Foundation of China
Cited by
4 articles.
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