Synthetic Strategies for the Regioselective Functionalization of Tribenzotriquinacenes

Abstract

The rigid molecular scaffold of the tribenzotriquinacenes (TBTQs) has emerged as a versatile structural platform that possesses unique geometrical features and allows for an orthogonal arrangement of organic functional substituents or convex-concave interactions. In this review, we summarize and discuss important synthetic strategies for a regioselective functionalization at the four distinct positions of the TBTQ basic framework, namely, apical, bridgehead, ortho, and outer rim.1 Introduction2 Structure and Synthesis of TBTQs3 Bridgehead Functionalization4 Outer Rim Functionalization5 ortho-Functionalization6 Apical Functionalization7 Conclusion and Outlook