The Synthesis of Five-Membered N-Heterocycles by Cycloaddition of Nitroalkenes with (In)Organic Azides and Other 1,3-Dipoles

Abstract

AbstractCycloaddition reactions have emerged as rapid and powerful methods for constructing heterocycles and carbocycles. [3+2] Cyclo­additions of nitroalkenes with various 1,3-dipoles have been an interesting research area for many organic chemists. This review outlines the synthesis of N-substituted and NH-1,2,3-triazoles along with other five-membered N-heterocycles through cycloaddition reactions of nitro­alkenes.1 Introduction2 Synthesis of 1,2,3-Triazoles2.1 Synthesis of NH-1,2,3-Triazoles2.2 Synthesis of N-Substituted 1,2,3-Triazoles3 Synthesis of Pyrrolidines and Pyrroles4 Synthesis of Pyrazoles5 Conclusion