Affiliation:
1. Key Laboratory of Synthetic and Biological Colloids
Abstract
An efficient Pd(0)-catalyzed alkylarylation of N-alkyl-N-methacryloylbenzamides with alkyl iodides for the synthesis of isoquinoline-1,3-diones is described. A highlight of the method is its excellent functional-group tolerance. Mechanistic investigations suggest that a radical addition/cyclization process is probably involved in the sequences.
Funder
National Science Foundation of China
Natural Science Foundation of Jiangsu Province
Cited by
11 articles.
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