Targeting of the Tec Kinase ITK Drives Resolution of T Cell–Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis-Reference-Cited by-同舟云学术

Targeting of the Tec Kinase ITK Drives Resolution of T Cell–Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis

Published:2021-10 Issue:4 Volume:161 Page:1270-1287.e19
ISSN:0016-5085
Container-title:Gastroenterology
language:en
Short-container-title:Gastroenterology

Author:

Lechner Kristina^ORCID,Mott Stefanie,Al-Saifi Ragheed,Knipfer Lisa,Wirtz Stefan,Atreya Raja,Vieth Michael,Rath Timo,Fraass Tina,Winter Zoltan,August Avery,Luban Jeremy,Zimmermann Valérie S.,Weigmann Benno,Neurath Markus F.

Funder

Deutsche Forschungsgemeinschaft

Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg

Publisher

Elsevier BV

Subject

Gastroenterology,Hepatology

Reference48 articles.

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2. itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2;Siliciano;Proc Natl Acad Sci U S A,1992

3. Tuning T helper cell differentiation by ITK;Elmore;Biochem Soc Trans,2020

4. CD8(+) T cells require ITK-mediated TCR signaling for migration to the intestine;Cho;Immunohorizons,2020

5. The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine;Cho;Nat Commun,2019

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