A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2-Reference-Cited by-同舟云学术

A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2

Published:2017-06-27 Issue:15 Volume:1 Page:1181-1194
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Khalil Shadi¹^ORCID,Holy Maja¹,Grado Stephen¹,Fleming Robert²,Kurita Ryo³,Nakamura Yukio³⁴,Goldfarb Adam¹^ORCID

Affiliation:

1. Department of Pathology, University of Virginia School of Medicine, Charlottesville, VA;

2. Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, MO;

3. Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Japan; and

4. Faculty of Medicine, University of Tsukuba, Tsukuba, Japan

Abstract

Key Points Transferrin receptor 2 drives lysosomal delivery of transferrin in erythroid progenitors. Erythroid mitochondria specifically associate with lysosomes and are regulated by transferrin receptor 2.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/15/1181/878725/advances003772.pdf

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4. Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol;Richardson;Proc Natl Acad Sci USA,2010

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