Two distinct CXCR4 antagonists mobilize progenitor cells in mice by different mechanisms-Reference-Cited by-同舟云学术

Two distinct CXCR4 antagonists mobilize progenitor cells in mice by different mechanisms

Published:2017-10-10 Issue:22 Volume:1 Page:1934-1943
ISSN:2473-9529
Container-title:Blood Advances
language:en
Short-container-title:

Author:

Redpath Andia N.¹^ORCID,François Moïra¹,Wong Suet-Ping¹,Bonnet Dominique²,Rankin Sara M.¹

Affiliation:

1. Inflammation, Repair, and Development Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom; and

2. Laboratoire d’Innovation Thérapeutique, UMR7200, Centre National de la Recherche Scientifique/Université de Strasbourg, LabEx Medalis, Faculté de Pharmacie, Illkirch, France.

Abstract

Key Points CXCR4 antagonist AMD3100 but not KRH3955 reverses the CXCL12 chemokine gradient across the bone marrow endothelium. CXCR4 antagonists mobilize stem cells from the bone marrow by distinct mechanisms.

Publisher

American Society of Hematology

Subject

Hematology

Link

http://ashpublications.org/bloodadvances/article-pdf/1/22/1934/877764/advances006064.pdf

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